Eunike Adabella, Cindy A. W. Oei, Vania A. Rantetasak, Tutuk Budiati, Ami Soewandi
In the present study, bis-(hydroxyben-zylidene)cycloalkanone derivatives were synthesized by Claisen – Schmidt condensation using cycloalkanones and arylaldehydes in the presence of HCl as an acid catalyst. The synthetic reaction was carried out under microwave irradiation. The structure of the synthesized compounds was determined by UV, IR,1H NMR spectroscopic methods. The obtained reaction yields were not optimal due to the self-polymerization of p-hydroxybenzaldehyde in an acid solution. © Adabella E., Oei C.A.W., Rantetasak V.A., Budiati T., Soewandi A., 2024.
Faculty of Pharmacy, Widya Mandala Catholic University Surabaya, Jl. Kalisari Selatan No.1 Kalisari, Pakuwon City, Kec. Mulyorejo, Jawa Timur, Surabaya, 60112, Indonesia