Rapid solvent-free microwave assisted synthesis of some N'-benzylidene salicylic acid hydrazides

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Tutuk Budiati, D.A. Stephanie, Elisabeth C. Widjajakusuma

2012 Indonesian Journal of Chemistry Vol. 12 Issue 2 Article Cited by 9 Quartile

Abstract

Condensation reaction has been carried out for the synthesis of some N'-benzylidene-2- hydroxybenzohydrazides using microwave assisted solvent-free method. The structures of all the products obtained in the present work are supported by spectral and analytical data (UV, IR, and 1H-NMR spectroscopy). The desired hydrazides are in 62-80% yields under microwave irradiation. The reaction was completed in 8-10 min.

Affiliations

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Airlangga University, Surabaya 60286, Jl. Dharmawangsa Dalam Selatan, Indonesia; Faculty of Pharmacy, Widya Mandala Catholic University, 42-44 Surabaya 60265, Jl. Dinoyo, Indonesia