Khafidhotul Ilmiah, Irene Lingkan Parengkuan, Anny Setijo Rahaju, Gondo Mastutik, Wahjoe Djatisoesanto
Background: Bladder urothelial neoplasms were the most common type of tumor in the urinary tract. These tumors often recur and are progressive. Therefore, it is necessary to analyze the patient’s profile. The aim is to examine the clinicopathologic character with a retrospective study. Method: This is a descriptive study with retrospective approach. Data were collected from the histopathological diagnosis of urothelial neoplasms at Laboratory of Anatomical Pathology in Dr. Soetomo General Academic Hospital, Surabaya, from 2013 to 2023. Result: There were 618 people with bladder urothelial neoplasms. Males predominate in this research (87.5%), and 32% occur between the ages of 51 and 60. Procedure used for diagnosing was 46.6% by TURB. High-grade tumors constituted 81% and 92.6% were already invasive, with 58.4% being MIBC. Discussion: This study exhibits a higher prevalence of urothelial neoplasms in males, likely due to smoking and androgen receptor influence. Most individuals were diagnosed after 50 years old. The majority of them already have high-grade, muscle-invasive tumors, which may have worse prognosis than low-grade, NMIBC tumors. Conclusion: There was male predominance in urothelial bladder neoplasms. Most ages were after 50 years. The majority of tumors were high grade and already muscle invasive (at least pT2). © The Author(s) 2026
Department of Anatomical Pathology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia; Department of Anatomical Pathology, Faculty of Medicine, Widya Mandala Surabaya Catholic University, Surabaya, Indonesia; Department of Urology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
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