Pre-meal high-performance inulin supplementation reduce post-prandial glycaemic response in healthy subjects: A repeated single-arm clinical trial

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Hendy Wijaya, Yudy Tjahjono, Kuncoro Foe, Diga Albrian Setiadi, Elisabeth Kasih, Hevi Wihadmadyatami

2022 Diabetes and Metabolic Syndrome: Clinical Research and Reviews Vol. 16 Issue 1 Article Cited by 13 Quartile

Abstract

Background and aims: High-performance (HP) inulin, a dietary fiber consists of more than 10 fructose polymers, have been shown to reduce post-prandial glycaemic response (PPGR) and could prevent the occurrence of Type-2 diabetes mellitus (T2DM). Currently, there are no data on whether pre-meal HP inulin supplementation could decrease PPGR. Methods: 8 healthy adults consumed 20 g of formula that contain 60.2% inulin (w/w) dissolved in water. Blood glucose was measured in fasted participants and at 30–120 min after starting to eat a prepared meal. This test was repeated every week with different supplement formulas. Conclusion: pre-meal HP Inulin formula supplementation could suppress the post-prandial glycaemic response. © 2021 Diabetes India

Affiliations

Biomedical Laboratory, Faculty of Pharmacy, Widya Mandala Catholic University, Jl. Kalisari Selatan No.1, Kalisari, Mulyorejo, Surabaya, 60112, East Java, Indonesia; Faculty of Veterinary Science, Gadjah Mada University, Jalan Fauna 2, Sleman, Yogyakarta, 55281, Indonesia