Cecilia Putri Tedyanto, Laura Wihanto, Eric Hartono Tedyanto, Anak Agung Ayu Suryapraba Indradewi, Ni Made Susilawathi
Cryptococcal meningitis is a rare disease caused by Cryptococcus neoformans or Cryptococcus gatii as the fungal patho-gen in humans. The disease is highly prevalent in people living with human immunodeficiency virus (HIV) and is the major cause of mortality in an immunocompromised individual. This life-threatening disease does not often occur with specific signs and symptoms. We reported a case of an early adulthood HIV-infected patient with a mild headache and low-grade fever. There was no altered mental status or other significant specific manifestations. Blood examination, chest radiogra-phy, and computed tomography scan revealed no significant results. C. neoformans were isolated from a culture of the cerebrospinal fluid specimen as the conventional gold standard examination for cryptococcal meningitis. A positive result was confirmed in the India ink staining preparation. The patient was treated with fluconazole monotherapy for the induction and consolidation phase and showed a positive disease progression during observations. © 2024, Amaltea Medical Publishing House. All rights reserved.
Department of Microbiology and Parasitology, Faculty of Medicine, Universitas Katolik Widya Mandala Surabaya, Surabaya, Indonesia; Department of Neurology, Universitas Udayana, Bali, Denpasar, Indonesia