Shella Permatasari Santoso, Artik Elisa Angkawijaya, Yi-Hsu Ju, Felycia Edi Soetaredjo, Suryadi Ismadji, Aning Ayucitra
The binary complexes with the [M(Dhba)]− core and ternary complexes with [M(Dhba)(Nac)]3− core have been synthesized and characterized by physical and spectral analyses, where M is divalent metal (Mn2+, Co2+, Ni2+, Cu2+ or Zn2+) and Dhba and Nac are 2, 3-dihydroxybenzoic acid and N-acetylcysteine, respectively. The synthesized complexes are practical in biological applications since they are soluble in water. The synthesized complexes were found to possess enhanced antimicrobial activity, especially against Staphylococcus aureus, but reduced DPPH scavenging activity of Dhba. The binary and ternary complexes of Zn2+ were shown to possess the most remarkable properties thus their structures were further examined. Thermodynamic properties of the Zn2+ complexes in aqueous solution at various temperatures were also determined with an ionic strength of 0.15 mol/dm3 NaCl. © 2016 Taiwan Institute of Chemical Engineers
Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, 10607, Taiwan; Institute of Plant and Microbial Biology, Academia Sinica, Taipei, 11529, Taiwan; Department of Chemical Engineering, Widya Mandala Surabaya Catholic University Kalijudan 37, Surabaya, 60114, Indonesia