Elok Zubaidah, Yunita Khilyatun Nisak, Ike Susanti, Tri Dewanti Widyaningsih, Ignatius Srianta, Ihab Tewfik
This study investigated the immunomodulatory effects of turmeric and black tea kombucha in the experimental animal. The kombucha was administrated orally to non-infected as well as Salmonella typhi-infected Balb-C mice and samples were taken to study the in vivo immunomodulatory activity of the kombucha. Both turmeric and black tea kombucha enhanced the adaptive immune response (indicated by an increase in CD4+, TNFα, IFN-γ) and innate immune response (evidenced by a decrease of CD68 IL-6). Although both samples showed notable positive results, the in vivo immunomodulatory activity of turmeric kombucha was much pronounced compared to black tea kombucha. © 2021 Elsevier Ltd
Department of Food Science and Technology, Faculty of Agricultural Technology, Brawijaya University, Malang, East Java, Indonesia; Department of Food Technology, Faculty of Agricultural Technology, Widya Mandala Surabaya Catholic University, Jalan Dinoyo, 42-44, Surabaya, 60265, Indonesia; School of Life Sciences, University of Westminster, 115 New Cavendish Street, London, W1W 6UW, UK, United Kingdom